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Rather than raising NAD+ systemically (as NMN or NR supplementation does), NNMT inhibition preserves NAD+ specifically in the tissue where metabolic dysfunction is most pronounced a precision approach that appeals to researchers studying tissue-specific metabolic regulation

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The following groups of peopleare older adults vegans and vegetarians people with diabetes people with conditions that reduce vitamin B12 absorption, including celiac disease people who have had gastric bypass surgery people who are taking medicines such as chloramphenicol, proton pump inhibitors, or H2 blockers The results may be: High

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